ObjectiveMetabolic syndrome appears to be connected to the onset of breast cancer through two pathways: obesity determines a high concentration of aromatase; and also insulin resistance, the related hyperinsulinaemia and high levels of IGF-1 (which rules as a growth factor like gonadotropic factor creating a hyperoestrogenic state). The goal we aim to reach is to identify a group at higher risk of developing breast cancer and to provide them with lifestyle models in order to support primary prevention and to assist the lead time in breast cancer detection.MethodsWe set up a project stratifying women≥ 35 years old into three groups: women with borderline lesions and/or with familiarity; women with breast cancer; and healthy women without any breast pathology. Each woman, after consent, completed a questionnaire about personal and familial anamnesis and physical activity. For each woman, blood pressure …